Activity-dependent regulation of the BAX/BCL-2 pathway protects cortical neurons from apoptotic death during early development

During early brain development, homeostatic removal of cortical neurons is crucial and requires multiple control mechanisms. We investigated in the cerebral cortex of mice whether the BAX/BCL-2 pathway, an important regulator of apoptosis, is part of this machinery and how electrical activity might...

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Detalles Bibliográficos
Autores principales: Schroer, Jonas, Warm, Davide, De Rosa, Federico, Luhmann, Heiko J., Sinning, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239391/
https://www.ncbi.nlm.nih.gov/pubmed/37269320
http://dx.doi.org/10.1007/s00018-023-04824-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239391/
https://www.ncbi.nlm.nih.gov/pubmed/37269320
http://dx.doi.org/10.1007/s00018-023-04824-6

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