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Improvement of cryo-EM maps by simultaneous local and non-local deep learning

Cryo-EM has emerged as the most important technique for structure determination of macromolecular complexes. However, raw cryo-EM maps often exhibit loss of contrast at high resolution and heterogeneity over the entire map. As such, various post-processing methods have been proposed to improve cryo-...

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Detalles Bibliográficos
Autores principales: He, Jiahua, Li, Tao, Huang, Sheng-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239474/
https://www.ncbi.nlm.nih.gov/pubmed/37270635
http://dx.doi.org/10.1038/s41467-023-39031-1