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Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations

Identifying patients that are likely to respond to cancer immunotherapy is an important, yet highly challenging clinical need. Using 3139 patients across 17 different cancer types, we comprehensively studied the ability of two common copy-number alteration (CNA) scores—the tumor aneuploidy score (AS...

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Detalles Bibliográficos
Autores principales: Chang, Tian-Gen, Cao, Yingying, Shulman, Eldad D., Ben-David, Uri, Schäffer, Alejandro A., Ruppin, Eytan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239491/
https://www.ncbi.nlm.nih.gov/pubmed/37270587
http://dx.doi.org/10.1038/s41698-023-00408-6