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Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations
Identifying patients that are likely to respond to cancer immunotherapy is an important, yet highly challenging clinical need. Using 3139 patients across 17 different cancer types, we comprehensively studied the ability of two common copy-number alteration (CNA) scores—the tumor aneuploidy score (AS...
Autores principales: | Chang, Tian-Gen, Cao, Yingying, Shulman, Eldad D., Ben-David, Uri, Schäffer, Alejandro A., Ruppin, Eytan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239491/ https://www.ncbi.nlm.nih.gov/pubmed/37270587 http://dx.doi.org/10.1038/s41698-023-00408-6 |
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