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Membrane estrogen receptor α signaling modulates the sensitivity to estradiol treatment in a dose- and tissue- dependent manner

Estradiol (E2) affects both reproductive and non-reproductive tissues, and the sensitivity to different doses of E2 varies between tissues. Membrane estrogen receptor α (mERα)-initiated signaling plays a tissue-specific role in mediating E2 effects, however, it is unclear if mERα signaling modulates...

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Detalles Bibliográficos
Autores principales: Jiang, Yiwen, Horkeby, Karin, Henning, Petra, Wu, Jianyao, Lawenius, Lina, Engdahl, Cecilia, Gupta, Priti, Movérare-Skrtic, Sofia, Nilsson, Karin H., Levin, Ellis, Ohlsson, Claes, Lagerquist, Marie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239518/
https://www.ncbi.nlm.nih.gov/pubmed/37270592
http://dx.doi.org/10.1038/s41598-023-36146-9