Clinical application of next generation sequencing-based haplotype linkage analysis in the preimplantation genetic testing for germline mosaicisms

BACKGROUND: Preimplantation genetic testing (PGT) for monogenic disorders (PGT-M) for germline mosaicism was previously highly dependent on polymerase chain reaction (PCR)-based directed mutation detection combined with linkage analysis of short tandem repeats (STRs). However, the number of STRs is...

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Detalles Bibliográficos
Autores principales: Chen, Dongjia, Xu, Yan, Fu, Yu, Wang, Yali, Liu, Yuliang, Ding, Chenhui, Cai, Bing, Pan, Jiafu, Wang, Jing, Li, Rong, Guo, Jing, Zhang, Han, Zeng, Yanhong, Shen, Xiaoting, Zhou, Canquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239584/
https://www.ncbi.nlm.nih.gov/pubmed/37270548
http://dx.doi.org/10.1186/s13023-023-02736-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239584/
https://www.ncbi.nlm.nih.gov/pubmed/37270548
http://dx.doi.org/10.1186/s13023-023-02736-z

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