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Structural modification of resveratrol analogue exhibits anticancer activity against lung cancer stem cells via suppression of Akt signaling pathway

BACKGROUND: Compound with cancer stem cell (CSC)-suppressing activity is promising for the improvement of lung cancer clinical outcomes. Toward this goal, we discovered the CSC-targeting activity of resveratrol (RES) analog moscatilin (MOS). With slight structural modification from RES, MOS shows do...

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Detalles Bibliográficos
Autores principales: Thongsom, Sunisa, Racha, Satapat, Petsri, Korrakod, Ei, Zin Zin, Visuttijai, Kittichate, Moriue, Sohsuke, Yokoya, Masashi, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239606/
https://www.ncbi.nlm.nih.gov/pubmed/37270520
http://dx.doi.org/10.1186/s12906-023-04016-6