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EPAS1/HIF-2α Acts as an Unanticipated Tumor-Suppressive Role in Papillary Thyroid Carcinoma

BACKGROUND: Overexpression of hypoxia-inducible factors led to tumor angiogenesis and tumor progression. However, unlike HIF-1α, the role of EPAS1/HIF-2α in papillary thyroid carcinoma (PTC) was unknown. Here, we aimed to investigate the role of EPAS1/HIF-2α in PTC. MATERIAL AND METHODS: EPAS1/HIF-2...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Zhao, Jianguo, Zhao, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239627/
https://www.ncbi.nlm.nih.gov/pubmed/37284036
http://dx.doi.org/10.2147/IJGM.S409874