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Sirolimus Induced Toxic Optic Neuropathy

OBJECTIVE: To describe a case of optic neuropathy after prolonged sirolimus therapy in the setting of cardiac transplant. BACKGROUND: Sirolimus is an immunosuppressant that inhibits Mechanistic Target of Rapamycin (mTOR) and blocks T-cell activation and B-cell differentiation by preventing response...

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Detalles Bibliográficos
Autores principales: Pakravan, Parastou, Miri, Shahnaz, Lam, Byron L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239645/
https://www.ncbi.nlm.nih.gov/pubmed/37284436
http://dx.doi.org/10.2147/IMCRJ.S388481