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Lipopolysaccharide increases bitter taste sensitivity via epigenetic changes in Tas2r gene clusters

T2R bitter receptors, encoded by Tas2r genes, are not only critical for bitter taste signal transduction but also important for defense against bacteria and parasites. However, little is known about whether and how Tas2r gene expression are regulated. Here, we show that in an inflammation model mimi...

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Detalles Bibliográficos
Autores principales: Lin, Cailu, Jyotaki, Masafumi, Quinlan, John, Feng, Shan, Zhou, Minliang, Jiang, Peihua, Matsumoto, Ichiro, Huang, Liquan, Ninomiya, Yuzo, Margolskee, Robert F., Reed, Danielle R., Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239704/
https://www.ncbi.nlm.nih.gov/pubmed/37283808
http://dx.doi.org/10.1016/j.isci.2023.106920