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Lipopolysaccharide increases bitter taste sensitivity via epigenetic changes in Tas2r gene clusters
T2R bitter receptors, encoded by Tas2r genes, are not only critical for bitter taste signal transduction but also important for defense against bacteria and parasites. However, little is known about whether and how Tas2r gene expression are regulated. Here, we show that in an inflammation model mimi...
Autores principales: | Lin, Cailu, Jyotaki, Masafumi, Quinlan, John, Feng, Shan, Zhou, Minliang, Jiang, Peihua, Matsumoto, Ichiro, Huang, Liquan, Ninomiya, Yuzo, Margolskee, Robert F., Reed, Danielle R., Wang, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239704/ https://www.ncbi.nlm.nih.gov/pubmed/37283808 http://dx.doi.org/10.1016/j.isci.2023.106920 |
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