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CNTNAP2 intracellular domain (CICD) generated by γ-secretase cleavage improves autism-related behaviors

As the most prevalent neurodevelopmental disorders in children, autism spectrum disorders (ASD) are characterized by deficits in language development, social interaction, and repetitive behaviors or inflexible interests. Contactin associated protein like 2 (CNTNAP2), encoding a single transmembrane...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Cai, Fang, Lu, Renbin, Xing, Xiaoliang, Xu, Lu, Wu, Kunyang, Gong, Zishan, Zhang, Qing, Zhang, Yun, Xing, Mengen, Song, Weihong, Li, Jia-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239753/
https://www.ncbi.nlm.nih.gov/pubmed/37271769
http://dx.doi.org/10.1038/s41392-023-01431-6