Alterations in the gut microbiota and serum metabolomics of spontaneous cholestasis caused by loss of FXR signal in mice

Background: Farnesoid X receptor (FXR) is a key metabolic target of bile acids (BAs) and is also a target for drugs against several liver diseases. However, the contribution of FXR in the pathogenesis of cholestasis is still not fully understood. The purpose of this study is to provide a comprehensi...

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Detalles Bibliográficos
Autores principales: Wei, Shizhang, He, Tingting, Zhao, Xu, Jing, Manyi, Li, Haotian, Chen, Lisheng, Zheng, Ruimao, Zhao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239812/
https://www.ncbi.nlm.nih.gov/pubmed/37284301
http://dx.doi.org/10.3389/fphar.2023.1197847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239812/
https://www.ncbi.nlm.nih.gov/pubmed/37284301
http://dx.doi.org/10.3389/fphar.2023.1197847

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