Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D

Complement factor D (FD) is a serine protease present predominantly in the active form in circulation. It is synthesized as a zymogen (pro-FD), but it is continuously converted to FD by circulating active MASP-3. FD is a unique, self-inhibited protease. It has an extremely low activity toward free f...

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Detalles Bibliográficos
Autores principales: Dani, Ráhel, Oroszlán, Gábor, Martinusz, Róbert, Farkas, Bence, Dobos, Bernadett, Vadas, Evelin, Závodszky, Péter, Gál, Péter, Dobó, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239819/
https://www.ncbi.nlm.nih.gov/pubmed/37283768
http://dx.doi.org/10.3389/fimmu.2023.1197023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239819/
https://www.ncbi.nlm.nih.gov/pubmed/37283768
http://dx.doi.org/10.3389/fimmu.2023.1197023

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