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Genetically predicted vitamin C levels significantly affect patient survival and immunotypes in multiple cancer types

BACKGROUND: Recent observational studies and meta-analyses have shown that vitamin C reduces cancer incidence and mortality, but the underlying mechanisms remain unclear. We conducted a comprehensive pan-cancer analysis and biological validation in clinical samples and animal tumor xenografts to und...

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Detalles Bibliográficos
Autores principales: Yuan, Jing, Zhang, Yu-hong, Hua, Xin, Hong, Hui-qi, Shi, Wei, Liu, Kun-xiang, Liu, Ze-xian, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239825/
https://www.ncbi.nlm.nih.gov/pubmed/37283769
http://dx.doi.org/10.3389/fimmu.2023.1177580