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Expression quantitative trait locus studies in the era of single-cell omics

Genome-wide association studies have revealed that the regulation of gene expression bridges genetic variants and complex phenotypes. Profiling of the bulk transcriptome coupled with linkage analysis (expression quantitative trait locus (eQTL) mapping) has advanced our understanding of the relations...

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Detalles Bibliográficos
Autores principales: Luo, Jie, Wu, Xinyi, Cheng, Yuan, Chen, Guang, Wang, Jian, Song, Xijiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239882/
https://www.ncbi.nlm.nih.gov/pubmed/37284065
http://dx.doi.org/10.3389/fgene.2023.1182579