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Role of anti-polyethylene glycol (PEG) antibodies in the allergic reactions to PEG-containing Covid-19 vaccines: Evidence for immunogenicity of PEG

A small fraction of recipients who receive polyethylene-glycol (PEG)-containing COVID-19 mRNA-LNP vaccines (Comirnaty and Spikevax) develop hypersensitivity reactions (HSRs) or anaphylaxis. A causal role of anti-PEG antibodies (Abs) has been proposed, but not yet been proven in humans. We used ELISA...

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Detalles Bibliográficos
Autores principales: Kozma, Gergely Tibor, Mészáros, Tamás, Berényi, Petra, Facskó, Réka, Patkó, Zsófia, Oláh, Csaba Zs., Nagy, Adrienne, Fülöp, Tamás Gyula, Glatter, Kathryn Anne, Radovits, Tamás, Merkely, Béla, Szebeni, János
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239905/
https://www.ncbi.nlm.nih.gov/pubmed/37330369
http://dx.doi.org/10.1016/j.vaccine.2023.06.009