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[(18)F]AlF-NOTA-ADH-1: A new PET molecular radiotracer for imaging of N-cadherin-positive tumors

BACKGROUND: The cell adhesion molecule (CAM) N-cadherin has become an important target for tumor therapy. The N-cadherin antagonist, ADH-1, exerts significant antitumor activity against N-cadherin-expressing cancers. METHODS: In this study, [(18)F]AlF-NOTA-ADH-1 was radiosynthesized. An in vitro cel...

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Detalles Bibliográficos
Autores principales: Liu, Zhenfeng, Wen, Guanghua, Huang, Yuqiao, Dong, Yanzhao, Wang, Zewei, Alhaskawi, Ahmad, Zhang, Shuyi, Wang, GuoLin, Ye, Qianni, Zhou, Haiying, Lu, Hui, Dong, Mengjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239968/
https://www.ncbi.nlm.nih.gov/pubmed/37284201
http://dx.doi.org/10.3389/fonc.2023.1126721