A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB signaling

An optimal intranasal (IN) dose of human mesenchymal stem cell-derived extracellular vesicles (hMSC-EVs), 90 min post-traumatic brain injury (TBI), has been reported to prevent the evolution of acute neuroinflammation into chronic neuroinflammation resulting in the alleviation of long-term cognitive...

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Detalles Bibliográficos
Autores principales: Kodali, Maheedhar, Madhu, Leelavathi N., Reger, Roxanne L., Milutinovic, Bojana, Upadhya, Raghavendra, Attaluri, Sahithi, Shuai, Bing, Shankar, Goutham, Shetty, Ashok K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239975/
https://www.ncbi.nlm.nih.gov/pubmed/37284464
http://dx.doi.org/10.3389/fnmol.2023.1185883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239975/
https://www.ncbi.nlm.nih.gov/pubmed/37284464
http://dx.doi.org/10.3389/fnmol.2023.1185883

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