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Altered cytoplasmic and nuclear ADP‐ribosylation levels analyzed with an improved ADP‐ribose binder are a prognostic factor in renal cell carcinoma

ADP‐ribosylation (ADPR) of proteins is catalyzed by ADP‐ribosyltransferases, which are targeted by inhibitors (i.e. poly(ADP‐ribose) polymerase inhibitors [PARPi]). Although renal cell carcinoma (RCC) cells are sensitive in vitro to PARPi, studies on the association between ADPR levels and somatic l...

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Detalles Bibliográficos
Autores principales: Schraml, Peter, Aimi, Fabio, Zoche, Martin, Aguilera‐Garcia, Domingo, Arnold, Fabian, Moch, Holger, Hottiger, Michael O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240151/
https://www.ncbi.nlm.nih.gov/pubmed/36999983
http://dx.doi.org/10.1002/cjp2.320