Resting natural killer cell homeostasis relies on tryptophan/NAD (+) metabolism and HIF‐1α

Natural killer (NK) cells are forced to cope with different oxygen environments even under resting conditions. The adaptation to low oxygen is regulated by oxygen‐sensitive transcription factors, the hypoxia‐inducible factors (HIFs). The function of HIFs for NK cell activation and metabolic rewiring...

Descripción completa

Detalles Bibliográficos
Autores principales: Pelletier, Abigaelle, Nelius, Eric, Fan, Zheng, Khatchatourova, Ekaterina, Alvarado‐Diaz, Abdiel, He, Jingyi, Krzywinska, Ewelina, Sobecki, Michal, Nagarajan, Shunmugam, Kerdiles, Yann, Fandrey, Joachim, Gotthardt, Dagmar, Sexl, Veronika, de Bock, Katrien, Stockmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240188/
https://www.ncbi.nlm.nih.gov/pubmed/36987917
http://dx.doi.org/10.15252/embr.202256156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240188/
https://www.ncbi.nlm.nih.gov/pubmed/36987917
http://dx.doi.org/10.15252/embr.202256156

Ejemplares similares