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Resting natural killer cell homeostasis relies on tryptophan/NAD (+) metabolism and HIF‐1α
Natural killer (NK) cells are forced to cope with different oxygen environments even under resting conditions. The adaptation to low oxygen is regulated by oxygen‐sensitive transcription factors, the hypoxia‐inducible factors (HIFs). The function of HIFs for NK cell activation and metabolic rewiring...
Autores principales: | Pelletier, Abigaelle, Nelius, Eric, Fan, Zheng, Khatchatourova, Ekaterina, Alvarado‐Diaz, Abdiel, He, Jingyi, Krzywinska, Ewelina, Sobecki, Michal, Nagarajan, Shunmugam, Kerdiles, Yann, Fandrey, Joachim, Gotthardt, Dagmar, Sexl, Veronika, de Bock, Katrien, Stockmann, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240188/ https://www.ncbi.nlm.nih.gov/pubmed/36987917 http://dx.doi.org/10.15252/embr.202256156 |
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