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Large‐scale heparin‐based bind‐and‐elute chromatography identifies two biologically distinct populations of extracellular vesicles

Purifying extracellular vesicles (EVs) has been challenging because EVs are heterogeneous in cargo yet share similar sizes and densities. Most surface marker‐based affinity separation methods are limited to research or diagnostic scales. We report that heparin chromatography can separate purified EV...

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Detalles Bibliográficos
Autores principales: Zhou, Yijun, Yuan, Runjie, Cone, Allaura S., Shifflett, Kyle W., Arias, Gabriel F., Peng, Alice, Chambers, Meredith G., McNamara, Ryan P., Willcox, Smaranda, Landis, Justin T., Pan, Yue, Griffith, Jack, Dittmer, Dirk P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240191/
https://www.ncbi.nlm.nih.gov/pubmed/37272197
http://dx.doi.org/10.1002/jev2.12327