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A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength
Argonaute (AGO) proteins use microRNAs (miRNAs) and small interfering RNAs (siRNAs) as guides to regulate gene expression in plants and animals. AGOs that use miRNAs in bilaterian animals recognize short (6–8 nt.) elements complementary to the miRNA seed region, enabling each miRNA to interact with...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240194/ https://www.ncbi.nlm.nih.gov/pubmed/37082939 http://dx.doi.org/10.15252/embr.202255806 |