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UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis

PLK1 is an important regulator of mitosis whose protein levels and activity fluctuate during the cell cycle. PLK1 dynamically localizes to various mitotic structures to regulate chromosome segregation. However, the signaling pathways linking localized PLK1 activity to its protein stability remain el...

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Detalles Bibliográficos
Autores principales: Guerber, Lucile, Vuidel, Aurore, Liao, Yongrong, Kleiss, Charlotte, Grandgirard, Erwan, Sumara, Izabela, Pangou, Evanthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240199/
https://www.ncbi.nlm.nih.gov/pubmed/37039032
http://dx.doi.org/10.15252/embr.202256241