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DOT1L regulates chromatin reorganization and gene expression during sperm differentiation

Spermatozoa have a unique genome organization. Their chromatin is almost completely devoid of histones and is formed instead of protamines, which confer a high level of compaction and preserve paternal genome integrity until fertilization. Histone‐to‐protamine transition takes place in spermatids an...

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Detalles Bibliográficos
Autores principales: Blanco, Mélina, El Khattabi, Laila, Gobé, Clara, Crespo, Marion, Coulée, Manon, de la Iglesia, Alberto, Ialy‐Radio, Côme, Lapoujade, Clementine, Givelet, Maëlle, Delessard, Marion, Seller‐Corona, Ivan, Yamaguchi, Kosuke, Vernet, Nadège, Van Leeuwen, Fred, Lermine, Alban, Okada, Yuki, Daveau, Romain, Oliva, Rafael, Fouchet, Pierre, Ziyyat, Ahmed, Pflieger, Delphine, Cocquet, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240200/
https://www.ncbi.nlm.nih.gov/pubmed/37099396
http://dx.doi.org/10.15252/embr.202256316