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Systemic depletion of WWP1 improves insulin sensitivity and lowers triglyceride content in the liver of obese mice

Obesity is a metabolic disorder associated with many diseases. WW domain‐containing E3 ubiquitin protein ligase 1 (WWP1) is a HECT‐type E3 ubiquitin ligase involved in several diseases. Recently, we found that the level of WWP1 is increased in white adipose tissue in a mouse model of obesity and tha...

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Detalles Bibliográficos
Autores principales: Nozaki, Yuka, Kobayashi, Masaki, Wakasawa, Hiroki, Hoshino, Shunsuke, Suwa, Fumika, Ose, Yuko, Tagawa, Ryoma, Higami, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240335/
https://www.ncbi.nlm.nih.gov/pubmed/37032433
http://dx.doi.org/10.1002/2211-5463.13610