Nitric oxide hinders club cell proliferation through Gdpd2 during allergic airway inflammation

Excessive nitric oxide (NO) is often observed in the airways of patients with severe asthma. Here, we show that the NO donor diethylamine NONOate impairs the proliferative capacity of mouse club cells and induces club cell apoptosis, cell cycle arrest, and alterations in lipid metabolism. Our data s...

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Detalles Bibliográficos
Autores principales: Yue, Qing, Li, Kuan, Song, Zhaoyu, Wang, Qi, Wang, Jianhai, Li, Xue, Li, Yu, Zhang, Qiuyang, Zhu, Yu, Chen, Huaiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240343/
https://www.ncbi.nlm.nih.gov/pubmed/37078963
http://dx.doi.org/10.1002/2211-5463.13617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240343/
https://www.ncbi.nlm.nih.gov/pubmed/37078963
http://dx.doi.org/10.1002/2211-5463.13617

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