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MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4

Mitofusin‐2 (MFN2) is a transmembrane GTPase that regulates mitochondrial fusion and thereby modulates mitochondrial function. However, the role of MFN2 in lung adenocarcinoma remains controversial. Here, we investigated the effect of MFN2 regulation on mitochondria in lung adenocarcinoma. We found...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjing, Pan, Lifang, Zhang, Qiang, Zhao, Yanyan, Wang, Wenwen, Lin, Nengming, Zhang, Shirong, Wu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240348/
https://www.ncbi.nlm.nih.gov/pubmed/36877954
http://dx.doi.org/10.1002/2211-5463.13591