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Immuno-persistence of the different primary polio vaccine schedules and immunogenicity of the booster dose by sabin inactivated or bivalent oral poliovirus vaccine in children aged 4 years: an open-label, randomised, controlled phase 4 trial in China

BACKGROUND: Sabin inactivated and bivalent oral poliovirus vaccine (sIPV, bOPV) were commonly used in China since 2016. We conducted an open-label, randomised, controlled phase 4 trial to assess immune persistence following sequential immunisation with sIPV or bOPV, and immunogenicity and safety of...

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Detalles Bibliográficos
Autores principales: Tang, Xuewen, Xiao, Yanhui, Deng, Xuan, Zhou, Yang, Chen, Haiping, Yan, Rui, Zhu, Yao, Wang, Shengyi, Wang, Hui, Zhu, Xiujuan, Luo, Linyun, Liu, Yan, Yin, Zhiying, Zhang, Guoping, Chen, Zhongbing, Jiang, Jian, Yang, Xiaoming, He, Hanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240380/
https://www.ncbi.nlm.nih.gov/pubmed/37283972
http://dx.doi.org/10.1016/j.lanwpc.2023.100725