Cargando…

Pregranulosa cell–derived FGF23 protects oocytes from premature apoptosis during primordial follicle formation by inhibiting p38 MAPK in mice

A large number of oocytes in the perinatal ovary in rodents get lost for unknown reasons. The granulosa cell–oocyte mutual communication is pivotal for directing formation of the primordial follicle; however, little is known if paracrine factors participate in modulating programmed oocyte death peri...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Zijian, Qin, Shaogang, Zhang, Tuo, He, Meina, Zheng, Wenying, Zhao, Ting, Gao, Meng, Chen, Ziqi, Zhou, Bo, Xia, Guoliang, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240423/
https://www.ncbi.nlm.nih.gov/pubmed/37142227
http://dx.doi.org/10.1016/j.jbc.2023.104776