Crosstalk of protein clearance, inflammasome, and Ca(2+) channels in retinal pigment epithelium derived from age-related macular degeneration patients

Degeneration and/or dysfunction of retinal pigment epithelium (RPE) is generally detected as the formation of intracellular and extracellular protein aggregates, called lipofuscin and drusen, respectively, in patients with age-related macular degeneration (AMD), the leading cause of blindness in the...

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Detalles Bibliográficos
Autores principales: Karema-Jokinen, Viivi, Koskela, Ali, Hytti, Maria, Hongisto, Heidi, Viheriälä, Taina, Liukkonen, Mikko, Torsti, Tommi, Skottman, Heli, Kauppinen, Anu, Nymark, Soile, Kaarniranta, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240424/
https://www.ncbi.nlm.nih.gov/pubmed/37137441
http://dx.doi.org/10.1016/j.jbc.2023.104770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240424/
https://www.ncbi.nlm.nih.gov/pubmed/37137441
http://dx.doi.org/10.1016/j.jbc.2023.104770

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