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Crosstalk of protein clearance, inflammasome, and Ca(2+) channels in retinal pigment epithelium derived from age-related macular degeneration patients
Degeneration and/or dysfunction of retinal pigment epithelium (RPE) is generally detected as the formation of intracellular and extracellular protein aggregates, called lipofuscin and drusen, respectively, in patients with age-related macular degeneration (AMD), the leading cause of blindness in the...
Autores principales: | Karema-Jokinen, Viivi, Koskela, Ali, Hytti, Maria, Hongisto, Heidi, Viheriälä, Taina, Liukkonen, Mikko, Torsti, Tommi, Skottman, Heli, Kauppinen, Anu, Nymark, Soile, Kaarniranta, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240424/ https://www.ncbi.nlm.nih.gov/pubmed/37137441 http://dx.doi.org/10.1016/j.jbc.2023.104770 |
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