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Vancomycin Concentrations in Synovial Fluid Do Not Reach Chondrotoxic Thresholds After Anterior Cruciate Ligament Reconstruction With Vancomycin-Soaked Autologous Soft Tissue Grafts: An In Vivo Prospective Observational Study in Humans

BACKGROUND: Studies have revealed that vancomycin soaking of the anterior cruciate ligament (ACL) graft can drastically reduce the incidence of postoperative infections after ACL reconstruction. However, it remains unknown whether the chondrotoxic threshold of vancomycin in synovial fluid is exceede...

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Detalles Bibliográficos
Autores principales: Pfeiffer, Thomas R., Althoff, Arne, Krombholz, Sophia, Dautert, Max, Naendrup, Jan-Hendrik, Guenther, Daniel, Bouillon, Bertil, Thevis, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240633/
https://www.ncbi.nlm.nih.gov/pubmed/37161935
http://dx.doi.org/10.1177/03635465231169040