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CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway

Chemotherapeutic agents remain the first-line treatment for solid tumors, including lung cancer, but chemotherapy resistance is hampering global efforts to treat this disease. CC-115 is a novel antitumoral compound used in phase I clinical trials. However, it is unclear whether CC-115 is effective a...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Liu, Ming-Quan, Xie, Guang-Su, Wu, Dong-Ming, Luo, Peng-Wei, Liu, Teng, Deng, Shi-Hua, Wang, Yuan-Yi, He, Shuang, Zhou, Ye, Zhou, Jin, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240660/
https://www.ncbi.nlm.nih.gov/pubmed/37283803
http://dx.doi.org/10.7150/jca.83175