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METTL14 suppresses cancer stem cell phenotype of colorectal cancer via regulating of β-catenin/NANOG

Cancer stem cell (CSC) characteristic contributes to tumor malignancy and progression. The role of N6-methyladenosine (m6A) modification in CSC characteristic is largely unknown. In this study, we found that m6A methyltransferase METTL14 was downregulated in colorectal cancer (CRC) and negatively co...

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Detalles Bibliográficos
Autores principales: Sun, Chun-Lei, Chen, Jiong, Xing, Zhi-Wei, Tao, Gong-Shai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240663/
https://www.ncbi.nlm.nih.gov/pubmed/37283789
http://dx.doi.org/10.7150/jca.82158