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PACAP6-38 improves nitroglycerin-induced central sensitization by modulating synaptic plasticity at the trigeminal nucleus caudalis in a male rat model of chronic migraine

AIMS: Chronic migraine (CM) is a common neurological disorder with complex pathogenesis. Evidence suggests that pituitary adenylate cyclase-activating peptide (PACAP) induces migraine-like attacks and may be potential a new target for migraine treatment, but the therapeutic results of targeting PACA...

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Detalles Bibliográficos
Autores principales: Zhang, Lily, Zhou, Yanjie, Yang, Liu, Wang, Yue, Xiao, Zheman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240775/
https://www.ncbi.nlm.nih.gov/pubmed/37271806
http://dx.doi.org/10.1186/s10194-023-01603-3