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Nicotine exacerbates atherosclerosis and plaque instability via NLRP3 inflammasome activation in vascular smooth muscle cells

Rationale: Nicotine has been reported to be a strong risk factor for atherosclerosis. However, the underlying mechanism by which nicotine controls atherosclerotic plaque stability remain largely unknown. Objective: The aim of this study was to evaluate the impact of lysosomal dysfunction mediated NL...

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Detalles Bibliográficos
Autores principales: An, Junqing, Ouyang, Liu, Yu, Changjiang, Carr, Sean Michael, Ramprasath, Tharmarajan, Liu, Zhixue, Song, Ping, Zou, Ming-Hui, Ding, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240824/
https://www.ncbi.nlm.nih.gov/pubmed/37284455
http://dx.doi.org/10.7150/thno.81388