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PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular aging

Aims: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that binds to low-density lipoprotein receptors. Efferocytosis is the process by which phagocytes remove apoptotic cells. Both PCSK9 and efferocytosis play important roles in regulating redox biology and inflammation, t...

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Detalles Bibliográficos
Autores principales: Liu, Shijie, Wu, Jinzi, Stolarz, Amanda, Zhang, Huiliang, Boerma, Marjan, Byrum, Stephanie D., Rusch, Nancy J, Ding, Zufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240829/
https://www.ncbi.nlm.nih.gov/pubmed/37284459
http://dx.doi.org/10.7150/thno.83914