Cargando…
PCSK9 attenuates efferocytosis in endothelial cells and promotes vascular aging
Aims: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that binds to low-density lipoprotein receptors. Efferocytosis is the process by which phagocytes remove apoptotic cells. Both PCSK9 and efferocytosis play important roles in regulating redox biology and inflammation, t...
Autores principales: | Liu, Shijie, Wu, Jinzi, Stolarz, Amanda, Zhang, Huiliang, Boerma, Marjan, Byrum, Stephanie D., Rusch, Nancy J, Ding, Zufeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240829/ https://www.ncbi.nlm.nih.gov/pubmed/37284459 http://dx.doi.org/10.7150/thno.83914 |
Ejemplares similares
-
Opinion: Endothelial Cells - Macrophage-Like Gatekeepers?
por: Stolarz, Amanda J., et al.
Publicado: (2022) -
NLRP3 inflammasome via IL-1β regulates PCSK9 secretion
por: Ding, Zufeng, et al.
Publicado: (2020) -
NLRP3 inflammasome via IL-1β regulates PCSK9 secretion: Erratum
por: Ding, Zufeng, et al.
Publicado: (2022) -
Defective efferocytosis of vascular cells in heart disease
por: Singh, Bandana, et al.
Publicado: (2022) -
PCSK9 Inhibitors Reduce PCSK9 and Early Atherogenic Biomarkers in Stimulated Human Coronary Artery Endothelial Cells
por: Zulkapli, Rahayu, et al.
Publicado: (2023)