Defining clonal hematopoiesis of indeterminate potential: evolutionary dynamics and detection under aging and inflammation

Clonal hematopoiesis (CH), in which hematopoietic stem and progenitor cell (HSPC) clones and their progeny expand in the circulating blood cell population, occurs following the acquisition of somatic driver mutations. Individuals diagnosed with clonal hematopoiesis of indeterminate potential (CHIP)...

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Detalles Bibliográficos
Autores principales: Goldman, Elisabeth A., Spellman, Paul T., Agarwal, Anupriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Mini-Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240836/
https://www.ncbi.nlm.nih.gov/pubmed/36889927
http://dx.doi.org/10.1101/mcs.a006251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240836/
https://www.ncbi.nlm.nih.gov/pubmed/36889927
http://dx.doi.org/10.1101/mcs.a006251

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