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Melanoma in a patient with DNMT3A overgrowth syndrome

Alterations in epigenetic regulators are increasingly recognized as early events in tumorigenesis; thus, patients with acquired or inherited variants in epigenetic regulators may be at increased risk for developing multiple types of cancer. DNMT3A overgrowth syndrome (DOS), caused by germline pathog...

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Detalles Bibliográficos
Autores principales: Chen, David Y., Sutton, Leslie A., Ramakrishnan, Sai Mukund, Duncavage, Eric J., Heath, Sharon E., Compton, Leigh A., Miller, Christopher A., Ley, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240841/
https://www.ncbi.nlm.nih.gov/pubmed/37160317
http://dx.doi.org/10.1101/mcs.a006267