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Spinal microRNA-134-5p targets glutamate receptor ionotropic kainate 3 to modulate opioid induced hyperalgesia in mice

Background: Fentanyl and its analogs are extensively used for pain relief. However, their paradoxically pronociceptive effects often lead to increased opioids consumption and risk of chronic pain. Compared to other synthetic opioids, remifentanil has been strongly linked to acute opioid hyperalgesia...

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Detalles Bibliográficos
Autores principales: Wang, Zhen, Yao, Yao, Tao, Yuzhu, Fan, Peixin, Yu, Yonghao, Xie, Keliang, Wang, Guolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240872/
https://www.ncbi.nlm.nih.gov/pubmed/37247385
http://dx.doi.org/10.1177/17448069231178271