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Spinal microRNA-134-5p targets glutamate receptor ionotropic kainate 3 to modulate opioid induced hyperalgesia in mice
Background: Fentanyl and its analogs are extensively used for pain relief. However, their paradoxically pronociceptive effects often lead to increased opioids consumption and risk of chronic pain. Compared to other synthetic opioids, remifentanil has been strongly linked to acute opioid hyperalgesia...
Autores principales: | Wang, Zhen, Yao, Yao, Tao, Yuzhu, Fan, Peixin, Yu, Yonghao, Xie, Keliang, Wang, Guolin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10240872/ https://www.ncbi.nlm.nih.gov/pubmed/37247385 http://dx.doi.org/10.1177/17448069231178271 |
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