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Palladium-catalyzed enantioselective three-component synthesis of α-arylglycine derivatives from glyoxylic acid, sulfonamides and aryltrifluoroborates

A palladium-catalyzed enantioselective three-component reaction of glyoxylic acid, sulfonamides and aryltrifluoroborates is described. This process provides modular access to the important α-arylglycine motif in moderate to good yields and enantioselectivies. The formed α-arylglycine products consti...

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Detalles Bibliográficos
Autores principales: Jakob, Bastian, Schneider, Nico, Gengenbach, Luca, Manolikakes, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241097/
https://www.ncbi.nlm.nih.gov/pubmed/37284589
http://dx.doi.org/10.3762/bjoc.19.52