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Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data
Variations of cell-type proportions within tissues could be informative of biological aging and disease risk. Single-cell RNA-sequencing offers the opportunity to detect such differential abundance patterns, yet this task can be statistically challenging due to the noise in single-cell data, inter-s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241145/ https://www.ncbi.nlm.nih.gov/pubmed/37277399 http://dx.doi.org/10.1038/s41467-023-39017-z |