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Downregulation of HAS-2 regulates the chondrocyte cytoskeleton and induces cartilage degeneration by activating the RhoA/ROCK signaling pathway

Osteoarthritis (OA) is a progressive joint disorder, which is principally characterized by the degeneration and destruction of articular cartilage. The cytoskeleton is a vital structure that maintains the morphology and function of chondrocytes, and its destruction is a crucial risk factor leading t...

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Detalles Bibliográficos
Autores principales: Yang, Junlong, Wang, Liu, Zhang, Zhongjie, Sun, Qing, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241152/
https://www.ncbi.nlm.nih.gov/pubmed/37232339
http://dx.doi.org/10.3892/ijmm.2023.5260