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STING is redundant for host defense and pathology of COVID-19-like disease in mice

Critical COVID-19 is characterized by lack of early type I interferon-mediated host defense and subsequent hyper-inflammation in the lungs. Aberrant activation of macrophages and neutrophils has been reported to lead to excessive activation of innate immunological pathways. It has recently been sugg...

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Detalles Bibliográficos
Autores principales: Marino, Giorgia, Zhang, Baocun, Schmitz, Alexander, Schwensen, Hanna VF, Reinert, Line S, Paludan, Søren R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241217/
https://www.ncbi.nlm.nih.gov/pubmed/37277149
http://dx.doi.org/10.26508/lsa.202301997