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STING is redundant for host defense and pathology of COVID-19-like disease in mice
Critical COVID-19 is characterized by lack of early type I interferon-mediated host defense and subsequent hyper-inflammation in the lungs. Aberrant activation of macrophages and neutrophils has been reported to lead to excessive activation of innate immunological pathways. It has recently been sugg...
Autores principales: | Marino, Giorgia, Zhang, Baocun, Schmitz, Alexander, Schwensen, Hanna VF, Reinert, Line S, Paludan, Søren R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241217/ https://www.ncbi.nlm.nih.gov/pubmed/37277149 http://dx.doi.org/10.26508/lsa.202301997 |
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