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(1)H-MRS to evaluate improved triglyceride accumulation in idiopathic triglyceride deposit cardiomyovasculopathy after CNT-01 (tricaprin/trisdecanoin) administration

SUMMARY: Triglyceride deposit cardiomyovasculopathy (TGCV) is an intractable disease characterized by massive triglyceride (TG) accumulation in the myocardium and coronary arteries caused by genetic or acquired dysfunction of adipose TG lipase (ATGL). A phase IIa trial has been conducted involving p...

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Detalles Bibliográficos
Autores principales: Aikawa, Tatsuro, Sai, Eiryu, Kudo, Ayako, Kawaguchi, Yuko O, Takamura, Kazuhisa, Hiki, Makoto, Yokoyama, Takayuki, Miyazaki, Tetsuro, Fujimoto, Shinichiro, Shimada, Kazunori, Hirano, Ken-ichi, Daida, Hiroyuki, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10241237/
https://www.ncbi.nlm.nih.gov/pubmed/37096980
http://dx.doi.org/10.1530/EDM-22-0370